Alentis Therapeutics has secured $181.4 million in an oversubscribed Series D financing round to advance its antibody-drug conjugates targeting claudin-1 (CLDN1)-positive tumors and organ fibrosis. This funding, led by OrbiMed and supported by several investors, brings the total raised by the company to $366.4 million since its founding in 2018. Clinical data for its innovative therapies is expected within the next 12 to 18 months.
Septerna, a GPCR-focused biotech, raised $288 million in its IPO, pricing shares at $18 each, above the initial range. The company aims to advance its lead drug candidate, SEP-786, for hypoparathyroidism, with human testing underway and data expected in 2025. This marks a significant moment in a busy period for biotech IPOs, with Septerna being the 23rd this year.
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